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COUMADIN ANTI STROKE FREE

Research has shown that standardized dosing works well with this medication. Xarelto also does not need to have blood tests done to determine its blood levels. Xarelto has been found to be especially useful in people who struggle to maintain a consistent INR. By working on Factor Xa thrombin levels are reduced and the probability of clotting is decreased. It prevents coagulation by working on Factor Xa. Xarelto works by inhibiting one of the clotting factors in the blood.

This class appears to have a higher risks of bleeding complications than warfarinįactor Xa Inhibitors: Xarelto (rivaroxaban), Eliquis (apixaban).

There are no blood tests available to monitor the effects of direct thrombin inhibitors.

Pradaxa does not require routine monitoring.

Pradaxa is an oral, prescription blood-thinning medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation (AFib) not caused by a heart valve problem.

Some direct thrombin inhibitors can be used to treat heparin induced thrombocytopenia.

(Currently, there is no standardized test available to measure the anticoagulant effects of this class of drugs.) The largest problem with this class of drugs is the high risk of bleeding complications. The benefit of Pradaxa is that it does not require routine blood monitoring. Pradaxa is a recently approved medication and is affective for stroke prophylaxis and atrial fibrillation. Dabigatran (Pradaxa) is the most common of this class. Argatroban is a treatment option when a patient experiences a very rare, life threatening complication of heparin known as heparin-induced thrombocytopenia. They are administered by injection and are not used for long term anitcoagulation. Bivalent DTIs may be used in circumstances in which heparin is indicated but not available as an option. They can bind to thrombin on the active site (univalent) or on both the active site and exosite 1 (bivalent). There are two ways in which direct thrombin inhibitors act. It activates many of the clotting factors, including Factor V. Thrombin is a protein that is involved in clotting. They work by binding to the thrombin molecule. The direct thrombin inhibitor class has some of the newest anticoagulants on the market.

COUMADIN ANTI STROKE FREE

One, it significantly reduces bruising and you won't find yourself running out of bruise free places to inject in a week.ĭirect Thrombin Inhibitors: Pradaxa (dabigatran), hirudin, bivalirudin, lepirudin, desirudin, argatroban You can also ice after, but icing before is really key.

The main thing I stress is ICE before the shot. Tips on giving yourself low molecular weight heparin shots.For more detailed directions, see the link below. You may consider icing it longer if you have a very sore, large bruise. If the location is sore, ice it for an additional period after the injection.

This will help to stop any subcutaneous bleeding. After the injection is done, put pressure on the site for at least 10-15 seconds. The ice will lessen the pain from the injection and it will also prevent the bruising. Ice the area for the injection until it is nice and numb.

There are some ways to minimize this side effect. Low molecular weight heparins cause deep bruises where the shot is given. The down side is that this class is very new and is high cost. One of the best parts of these medications is that the patient does not need blood tests to assess blood levels. It can be used as a prophylactic before a long haul flight or car trip to prevent clots, it can be used during pregnancy to help someone with a clotting condition to carry the baby to term without complications, and it can be used as a bridge therapy so that warfarin is cleared out of the body prior to surgery. This drug class has some additional unique uses. LMWH also can be used as a stand alone treatment or prevention of blood clots. This will prevent clots during the beginning of warfarin anticoagulation. LMWH can be used when a patient is starting a warfarin regimen. The needle on my pre-filled Lovenox syringes were very sharp and went in smoothly without effort. Some people may feel squeamish about self-injecting. They can be done at home and can come in vials or pre-filled syringes. All of these drugs are administered by injection. Some examples in this class are Normiflo (ardeparin), Fragmin (dalteparin), Orgarin (danaparoid), Lovenox (enoxaparin), and Innohep (tinzaparin). Low molecular weight heparins (LMWH) also fall under the anticoagulant category. Low molecular weight heparins: Normiflo (ardeparin), Fragmin (dalteparin), Orgarin (danaparoid), Lovenox (enoxaparin), Innohep (tinzaparin) A Lovenox syringe from A Boy and His Bike on Flickr.